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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2C
All Species:
19.09
Human Site:
S459
Identified Species:
35
UniProt:
Q06413
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06413
NP_002388.2
473
51221
S459
P
S
P
D
E
R
E
S
P
S
V
K
R
M
R
Chimpanzee
Pan troglodytes
XP_001139828
503
54271
E489
P
P
N
T
E
D
R
E
S
P
S
V
K
R
M
Rhesus Macaque
Macaca mulatta
XP_001086412
483
52310
S469
P
S
P
D
E
R
E
S
P
S
V
K
R
M
R
Dog
Lupus familis
XP_858441
472
51065
S458
P
S
P
D
E
R
E
S
P
S
V
K
R
M
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFN5
474
51260
E459
R
P
S
P
D
E
R
E
S
P
S
V
K
R
M
Rat
Rattus norvegicus
Q2MJT0
495
53235
E481
P
P
N
A
E
D
R
E
S
P
S
V
K
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510456
503
54885
S489
P
S
P
D
E
R
E
S
P
S
V
K
R
M
R
Chicken
Gallus gallus
Q9W6U8
499
53650
E485
P
P
N
S
E
D
R
E
S
P
S
V
K
R
M
Frog
Xenopus laevis
Q03413
498
54053
L474
D
Y
T
S
S
L
G
L
L
R
P
S
G
D
T
Zebra Danio
Brachydanio rerio
NP_571387
465
49956
S450
A
A
E
N
E
R
Q
S
P
S
V
K
R
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
V507
V
R
L
A
A
V
A
V
Q
Q
Q
Q
Q
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
L254
E
R
G
D
Q
S
S
L
A
N
S
P
P
E
A
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
S439
V
F
P
S
S
V
A
S
S
T
L
K
S
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.4
93.3
99.1
N.A.
98.7
56.5
N.A.
93
63.1
56.6
79.4
N.A.
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
74.3
94.8
99.3
N.A.
99.7
69.2
N.A.
94
74.1
70.4
88.5
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
0
13.3
N.A.
100
13.3
0
66.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
13.3
20
N.A.
100
20
0
86.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
16
8
0
16
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
39
8
24
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
0
8
0
62
8
31
31
0
0
0
0
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
47
31
0
0
% K
% Leu:
0
0
8
0
0
8
0
16
8
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
31
% M
% Asn:
0
0
24
8
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
54
31
39
8
0
0
0
0
39
31
8
8
8
0
8
% P
% Gln:
0
0
0
0
8
0
8
0
8
8
8
8
8
8
0
% Q
% Arg:
8
16
0
0
0
39
31
0
0
8
0
0
39
31
39
% R
% Ser:
0
31
8
24
16
8
8
47
39
39
39
8
8
0
8
% S
% Thr:
0
0
8
8
0
0
0
0
0
8
0
0
0
8
8
% T
% Val:
16
0
0
0
0
16
0
8
0
0
39
31
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _